Featured Articles
Can Asthma Damage Be Reversed? A New Era of Treatment Is Challenging Old Assumptions
For generations, asthma has been understood primarily as a disease of inflammation. During an asthma attack, immune cells flood the airways, muscles tighten, mucus accumulates, and breathing becomes difficult. But beneat…
Read more
The Tolerance-Breaking Continuum: From Barrier Injury to Systemic Autoimmunity
A diabetes experiment points toward a larger goal in medicine: understanding how immune tolerance breaks, and whether it can be rebuilt The human immu…
Read more
Chronic Hives May Be a Window Into a Larger Inflammatory Disorder
A patient walks into an allergy clinic because of hives. The skin is covered with raised, itching welts that appear, disappear, and migrate unpredicta…
Read more
Articles
Aerosol or Powder? Why the Type of Inhaler Can Change Where Asthma and COPD Medicine Goes
Some inhalers spray medicine into the airways, whereas others depend on the patient's breath to turn a powder into inhalable particles. That seemingly simple di…
Read more
What Happens When You Stop an Antihistamine? Not All Withdrawal Reactions Are the Same
Benadryl, Zyrtec and Xyzal are familiar over-the-counter medicines, but reports of symptoms after stopping them reveal two very different ways the nervous and i…
Read more
When Allergy Cells Invade the Bladder, an Asthma Drug May Help
When bladder inflammation resembles infection or cancer Blood in the urine, pelvic pain and a relentless need to urinate usually prompt a search for infection,…
Read more
Immune Cells Living in the Lungs May Help Explain Genetic Risk for Asthma, COPD and Autoimmune Disease
An analysis of more than one million human immune cells suggests that inherited risk for asthma, COPD and autoimmune disease may be expressed in cells that rema…
Read more
Can Asthma Be Stopped Before It Leaves Permanent Scars? How Anti-IgE Therapy May Change the Disease Itself
For decades, asthma treatment has focused on controlling symptoms, reducing flare-ups, and preserving lung function. Yet many people with persistent allergic as…
Read more
Can Autoimmunity Be Reversed?
An experimental cell therapy reversed newly developed type 1 diabetes in mice by strengthening the immune system’s peacekeepers and persuading its attackers to…
Read more
Rise of Climate-Driven Fungal Diseases
There is an old joke among infectious disease specialists that fungi are "the forgotten kingdom." They lack the explosive headlines of viruses, the noto…
Read more
The Airway's Early Warning System: How the Lining of Your Lungs Decides Whether You Stay Healthy, or Develop Asthma
For decades, asthma was viewed primarily as a disorder of overactive immune cells. Doctors focused on eosinophils, IgE antibodies, mast cells, and the inflammat…
Read more
Chronic Hives Are More Than a Skin Problem: The Immune Signals Behind Itching, Swelling, and Treatment Response
For someone with chronic spontaneous urticaria, or CSU, the day can begin with clear skin and end with raised, intensely itchy welts covering the arms, legs, or…
Read more
The Forgotten Fungi in a Baby’s Gut: Could They Influence Allergy Risk Years Later?
For years, the story of the infant microbiome has been told largely through bacteria. Scientists have linked early bacterial communities to everything from dige…
Read more